PRECISION DRUG DELIVERY

Engineering how drugs

reach the immune system.

Gyldenpharma operates two distinct, partnerable delivery platforms: gold nanoparticle peptide vaccines for oncology and infectious disease, and a microneedle patch system with a near-term NDA asset in chronic migraine.

TWO PLATFORMS. ONE COMPANY

Distinct technologies.

Shared delivery expertise.

Each platform operates independently as a licensable technology with proprietary programs. Both benefit from Gyldenpharma’s core competence in precision intradermal and immune-targeted delivery — and each is available for strategic partnership.

PLATFORM I

PLATFORM II

AuNP Peptide Vaccine Platform

Ultra-small (3–5 nm) gold nanoparticles decorated with sugar moieties for self-adjuvanting activity, carrying multiple CD8 and CD4 T cell epitopes. Designed as a direct alternative to mRNA-LNP approaches — with superior stability, no cold chain, and no requirement for cellular translation.

Microneedle Patch Delivery Platform

Microneedle arrays for painless, reproducible intradermal delivery of small molecules, peptides, and biologics. Lead asset: zolmitriptan patch for chronic migraine, NDA-resubmission ready following FDA Type C and forthcoming Type D meeting alignment. Platform extendable to other partner compounds.

BUSINESS MODEL

A platform licensing company with proprietary programs.

Both platforms are available as licensable technology assets, providing partners with established IP, device, and regulatory packages. Gyldenpharma retains equity stakes in co-development programs.